Project 2: Mechanisms of Polycyclic Aromatic Hydrocarbon-linked Immunopathogenesis in Atopy

There are many environmental factors that contribute to disease in children. One of the most serious health outcomes in children is a dysregulated immune system, or an immune system that is not working properly. This project is studying the effects of air pollution on the immune system. Researchers are also examining how immune dysregulation leads to food allergy and other allergic disorders in children. Project 2 Investigates whether ambient air pollutant exposure is associated with risk of allergic disease (food allergy, atopic dermatitis, allergic rhinitis, allergic conjunctivitis and allergic asthma) with decrements in lung function during immune development in childhood.

Project Leaders: Kari C. Nadeau, M.D., Ph.D., Stanford University


What are Polycyclic Aromatic Hydrocarbons (PAHs)?